Cast
Cillian Murphy as J. Robert Oppenheimer, a theoretical physicist and director of the Los Alamos Laboratory
Emily Blunt as Katherine "Kitty" Oppenheimer, Robert Oppenheimer's wife and a former Communist Party USA member
Matt Damon as Gen. Leslie Groves, a United States Army Corps of Engineers (USACE) officer and director of the Manhattan Project
Robert Downey Jr. as Rear Admiral Lewis Strauss, a retired Naval Reserve officer and high-ranking member of the US Atomic Energy Commission (AEC)
Florence Pugh as Jean Tatlock, a psychiatrist, Communist Party USA member, and Robert Oppenheimer's romantic interest
Josh Hartnett as Ernest Lawrence, a Nobel-winning nuclear physicist who worked with Oppenheimer at the University of California, Berkeley
Casey Affleck as Boris Pash, a US Army military intelligence officer and commander of the Alsos Mission
Rami Malek as David L. Hill, a nuclear physicist at the Metallurgical Laboratory, who helped to create the Chicago Pile
Kenneth Branagh as Niels Bohr, a Nobel-winning Danish physicist, philosopher and Oppenheimer's personal idol
Benny Safdie as Edward Teller, a Hungarian theoretical physicist known for being the "father of the hydrogen bomb"
Jason Clarke as Roger Robb, an attorney and future US circuit judge who served as special counsel to the AEC at Oppenheimer's security hearing
Dylan Arnold as Frank Oppenheimer, Robert's younger brother and a particle physicist who worked on the Manhattan Project
Tom Conti as Albert Einstein, Nobel-winning German theoretical physicist known for developing the theory of relativity
James D'Arcy as Patrick Blackett, Oppenheimer's doctoral supervisor and Nobel-winning physicist at Cambridge University
David Dastmalchian as William L. Borden, a lawyer and executive director of the United States Congressional Joint Committee on Atomic Energy (JCAE)
Dane DeHaan as Maj Gen. Kenneth Nichols, a United States Army Corps of Engineers (USACE) and the deputy district engineer of the Manhattan Project
Alden Ehrenreich as a Senate aide to Lewis Strauss during Strauss's nomination for United States Secretary of Commerce
Tony Goldwyn as Gordon Gray, a government official and chairman of the committee deciding the revoking of Oppenheimer security clearance
Jefferson Hall as Haakon Chevalier ("Hoke"), a Berkeley professor who became friends with Oppenheimer at university, and was central to the Chevalier Incident
David Krumholtz as Isidor Isaac Rabi, a Nobel Prize-winning physicist who worked as a consultant on the Manhattan Project
Matthew Modine as Vannevar Bush, head of the Office of Scientific Research and Development
Scott Grimes as Counsel to Lewis Strauss
Kurt Koehler as Thomas A. Morgan, an industrialist and former chairman of the board of the Sperry Corporation who was one of the panel members at Oppenheimer's security clearance hearing
John Gowans as Ward V. Evans, a chemist and academic who served as one of the panel members at Oppenheimer's security clearance hearing
Macon Blair as Lloyd K. Garrison, a lawyer who helped to represent Oppenheimer at his security clearance hearing
Gregory Jbara as Sen. Warren Magnuson, Chairman of Senate Commerce Committee
Harry Groener as Sen. Gale W. McGee
Tim DeKay as Sen. John Pastore
Matthias Schweighöfer as Werner Heisenberg, a German Nobel Prize-winning physicist who worked in Germany's nuclear weapons program during World War II
Alex Wolff as Luis Walter Alvarez, a Nobel-winning physicist who worked on the Manhattan Project
Josh Zuckerman as Giovanni Rossi Lomanitz, a physicist who became Oppenheimer's protégé at Berkeley
Rory Keane as Hartland Snyder, a physicist, who collaborated with Oppenheimer to calculate the gravitational collapse of a dust particle sphere
Michael Angarano as Robert Serber, a physicist who worked on the Manhattan Project
Britt Kyle as Barbara Chevalier, Hoke's wife
Emma Dumont as Jackie Oppenheimer, Frank's wife and Robert's sister-in-law
Guy Burnet as George C. Eltenton, a chemical engineer in the US with ties to the Soviet Union
Louise Lombard as Ruth Tolman, a psychologist close to Oppenheimer during the development of the atomic bomb
Tom Jenkins as Richard C. Tolman, Ruth's husband and General Groves' chief scientific adviser on the Manhattan Project
Olli Haaskivi as Edward Condon, a nuclear physicist who helped with the development of radar and briefly took part in the Manhattan Project
David Rysdahl as Donald Hornig, a chemist who worked on the firing unit at Los Alamos
Josh Peck as Kenneth Bainbridge, a physicist who was the director of the Manhattan Project's Trinity nuclear test
Jack Quaid as Richard Feynman, an American Nobel-winning theoretical physicist who worked in the Theoretical Division at Los Alamos
Gustaf Skarsgård as Hans Bethe, a German-American Nobel-winning theoretical physicist and the head of the Theoretical Division at Los Alamos
James Urbaniak as Kurt Gödel, an Austrian logician and mathematician known for his theorems that revolutionized mathematics and had far-reaching implications for philosophy and computer science
Trond Fausa as George Kistiakowsky, a Ukrainian-born Harvard professor who took part in the Manhattan Project
Devon Bostick as Seth Neddermeyer, a physicist who discovered the muon and advocated for the implosion-type nuclear weapon used in the Trinity Test
Danny Deferrari as Enrico Fermi, an Italian Nobel-winning physicist and creator of the Chicago Pile
Christopher Denham as Klaus Fuchs, a German-born physicist who worked on the Manhattan Project and spied for the Soviet Union
Jessica Erin Martin as Charlotte Serber, head technical librarian at Los Alamos
Ronald Auguste as J. Ernest Wilkins Jr., an African American nuclear scientist, mechanical engineer and mathematician who worked with Oppenheimer on the Manhattan Project
Máté Haumann as Leo Szilard, a Hungarian physicist who conceived the idea of nuclear chain reaction in 1933, and later in July 1945 at the Chicago branch of the Manhattan Project circulated the petition to President Truman against unannounced use of atomic weapons on Japan
Olivia Thirlby as Lilli Hornig, a Czech-American scientist who worked on the Manhattan Project
Jack Cutmore-Scott as Lyall Johnson, a security officer at Berkeley who worked at the Manhattan Project
Harrison Gilbertson as Philip Morrison, a physics professor who worked on the Manhattan Project
James Remar as Henry L. Stimson, Secretary of War under President Truman
Will Roberts as George C. Marshall, the United States Army Chief of Staff from 1939 to 1945
Pat Skipper as James F. Byrnes, US Secretary of State and future Governor of South Carolina
Gary Oldman as Harry S. Truman, the 33rd President of the United States who made the decision to drop the two atomic bombs on Hiroshima and Nagasaki in August 1945
Hap Lawrence as Lyndon B. Johnson, the 36th President of the United States
Troy Bronson as Joseph W. Kennedy, a chemist instrumental in the discovery of plutonium, and head of the Chemistry Department at Los Alamos