Joséphine Missoffe (French pronunciation: [ʒozefin misɔf]; née Seillière de Laborde, 24 September 1973) is a French politician who has represented the 14th constituency of Paris in the National Assembly since 2024. A member of Renaissance (RE), she was elected as Benjamin Haddad's substitute in 2022 and 2024; she took his seat upon his appointment to the government.
She is the daughter of entrepreneur and heir Ernest-Antoine Seillière and the sister-in-law of politician Françoise de Panafieu.