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Dennis Brown

teacher

Dennis Brown

British renal physiologist

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About Dennis Brown

Dennis Brown is a renal physiologist. He is Professor of Medicine at Harvard Medical School, director of the Program in Membrane Biology at the Massachusetts General Hospital (MGH), and Associate Director of the MGH Center for Systems Biology. He is a member of the MGH Executive Committee on Research (ECOR), the central body for research governance at MGH.

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Occupation: teacher, researcher
Citizenship: United Kingdom

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Aquaporin Function: Seek and You Shall Find!Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells Inhibition of non-receptor tyrosine kinase Src induces phosphoserine 256-independent aquaporin-2 membrane accumulation Dmxl1 Is an Essential Mammalian Gene that Is Required for V-ATPase Assembly and Function In Vivo Ribosomal s6 kinase (RSK) is a mediator of aquaporin 2 S256 phosphorylation and membrane accumulation after EGFR inhibition with erlotinib Regulatory T cells play a crucial role in maintaining sperm tolerance and male fertility Knockout of the V-ATPase interacting protein Tldc2 in B-type kidney intercalated cells impairs urine alkalinization CX3CR1 deficiency leads to impairment of immune surveillance in the epididymis Harvard University Massachusetts General Hospital

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