Return to independents: 2009–present
With many of the stories he had planned for America's Best Comics brought to an end, and with his increasing dissatisfaction with how DC Comics were interfering with his work, he decided to once more pull out of the comics mainstream. In 2005, he remarked that "I love the comics medium. I pretty much detest the comics industry. Give it another 15 months, I'll probably be pulling out of mainstream, commercial comics." The only ABC title continued by Moore was The League of Extraordinary Gentlemen; after cutting ties with DC he launched the new League saga, Volume III: Century, in a co-publishing partnership of Top Shelf Productions and Knockabout Comics, the first part, titled "1910" released in 2009, the second, titled "1969", released in 2011, and the third, titled "2009", released in 2012. He continues to work with Kevin O'Neill on their League of Extraordinary Gentlemen spin-off, Nemo, with three graphic novels published, "Heart of Ice", "The Roses of Berlin" and "River of Ghosts".
In 2006, the complete edition of Lost Girls was published, as a slipcased set of three hardcover volumes. The same year Moore published an eight-page article tracing out the history of pornography in which he argued that a society's vibrancy and success are related to its permissiveness in sexual matters. Decrying that the consumption of contemporary ubiquitous pornography was still widely considered shameful, he called for a new and more artistic pornography that could be openly discussed and would have a beneficial impact on society. He expanded on this for a 2009 book-length essay entitled 25,000 years of Erotic Freedom, which was described by a reviewer as "a tremendously witty history lecture—a sort of Horrible Histories for grownups."
In 2007, Moore appeared in animated form in an episode of The Simpsons—a show of which he is a fan—entitled "Husbands and Knives", which aired on his fifty-fourth birthday.
Since 2009, Moore has been a panellist on the BBC Radio 4 programme The Infinite Monkey Cage, which is hosted by physicist Brian Cox and comedian Robin Ince.
In 2010, Moore began what he described as "the 21st century's first underground magazine". Titled Dodgem Logic, the bi-monthly publication consisted of work by a number of Northampton and Midlands-based authors and artists, as well as original contributions from Moore. Despite Dodgem Logic's content not being particularly regional or parochial, its advertising sales remained mainly Midland's based, limiting its financial stability, and making it unusually dependent upon sales revenues. It ran for eight issues and folded in April 2011.
In 2010 Moore began publishing a series of comics set in the H. P. Lovecraft universe returning to an earlier interest in the work and worlds of the author. Avatar Press had previously published Alan Moore's Yuggoth Cultures and Other Growths, a compilation of unpublished scripts and strips and comic adaptations of previously published poems by Moore themed around or based upon Lovecraft's work in 2003, followed by the two part The Courtyard adapted from a previously published Lovecraftian Moore short story. The horror miniseries Neonomicon, the first of Moore's original comic works released by Avatar Press, were illustrated by Jacen Burrows who had also illustrated the earlier adaptations, and the fourth and final issue was released in January 2011.
In 2014 a twelve-part series reuniting Moore with Jacen Burrows was announced titled Providence on Lovecraft and the sources of the Cthulhu Mythos forming a prequel to Neonomicon. It was published in twelve issues from 2015 to 2017.
Moore has appeared live at music events collaborating with a number of different musicians, including a 2011 appearance with Stephen O'Malley at the All Tomorrow's Parties 'I'll Be Your Mirror' music festival in London.
A planned future project is an occult textbook known as The Moon and Serpent Bumper Book of Magic, written with Steve Moore. It will be published by Top Shelf on 15 October 2024. In September 2016, he published a novel called Jerusalem, which is also set in Northampton.
Alan Moore has joined the Occupy Comics Kickstarter project. Moore contributed an essay on comics as counter-culture.
In 2014, Moore announced that he was leading a research and development project to "create an app enabling digital comics to be made by anyone". Electricomics premiered in 2015. It is an open source app for reading and creating interactive comics. Moore wrote the story Big Nemo, a dystopian sequel to Winsor McCay's Little Nemo. It was illustrated by Colleen Doran and animated by Ocasta Studios with colours by Jose Villarubia. The Guardian chose it as one of the best iPhone/iPad apps of 2015. Pipedream Comics named it the Digital Comics App of the Year.
In 2016, Moore confirmed that after authoring a final League of Extraordinary Gentlemen book, he planned on retiring from regularly writing comic books.
In April 2016, Moore began curating a comic book anthology series entitled Cinema Purgatorio published by Avatar Press, each issue opening with a story written by Moore and illustrated by Kevin O'Neill. The book also features the writing and artist team-ups of Garth Ennis and Raulo Cáceres (Code Pru), Max Brooks and Michael DiPascale (A More Perfect Union), Kieron Gillen and Ignacio Calero (Modded), and Christos Gage and Gabriel Andrade (The Vast). The anthology series has been described as "Classic tropes of pulp fiction, either turned on their head, given new filters or explored in ridiculous detail, by some of the very best comic creators we have today."
In 2018, Moore contributed to the comic anthology 24 Panels. The publication was curated by Kieron Gillen and intended to raise funds for those affected by the Grenfell Tower fire of 2017.
With the end of the fourth volume of League of Extraordinary Gentlemen, the conclusion of his Lovecraft sequence and some short stories appearing in Cinema Purgatorio, Moore has retired from comics as of mid-2019. In 2022 he confirmed it, saying "I'm definitely done with comics, I haven't written one for getting on for five years. I will always love and adore the comics medium but the comics industry and all of the stuff attached to it just became unbearable."
In 2021, it was announced that Moore was a writing a five-volume fantasy series titled Long London. The first book of the series, The Great When, was released on 1 October 2024, while the second book of the series is named as I Hear A New World.