2006–2008: Second reunion with Roth and Wolfgang Van Halen era
Rumors of a Roth reunion re-emerged and on January 3, 2006, Roth explained during an interview that he had spoken to Alex Van Halen the previous week and a reunion was "inevitable." However, he also said that Eddie Van Halen was "off in his own little world". When asked if any problems occurred with Hagar during the 2004 tour Eddie answered, "Sammy is Sammy, and for the most part that's just fine." Roth persisted with suggestions of a reunion, saying, "People want the reunion," and "No one will pay respect to what any of us do [musically] until we get the reunion out of the way." In May 2006, he told Billboard.com, "There's contact between the two camps."
On June 3, Anthony began a successful tour with Hagar billed as the Other Half (a reference to them being half of Van Halen with the other half being Eddie/Alex), with Anthony singing lead vocals sometimes. Meanwhile, on June 19 the Van Halen brothers jumped onstage with Kenny Chesney at The Home Depot Center performing "Jump" and "You Really Got Me". This unusual performance was their first onstage since the 2004 tour. This was followed by another Eddie performance on July 19, 2006, at the House of Petals in Los Angeles, playing new material. He followed this with an announcement on July 27, 2006, that some of his new music would be released on the soundtrack for the pornographic film Sacred Sin.
In March 2006, Anthony spoke to Japanese rock magazine Burrn!, claiming the brothers did not want him on the 2004 reunion tour, although Hagar did (and would not play without Anthony), but he had to agree to reduced royalties and end absolutely all association with the band after the tour in terms of rights to using the name to promote himself. In this same interview he admitted he was not involved in the new songs on Best of Both Worlds and only recorded three tracks for Van Halen III.
Anthony was replaced as bass player by Eddie's son, Wolfgang Van Halen, in 2006. On September 8, 2006, Howard Stern's live interview with Eddie broke the band's long silence. Eddie said he was willing to reunite with Roth and revealed a solo album in the works. Eddie confirmed that Wolfgang had replaced Anthony on bass; Wolfgang had played guitar alongside his father during Eddie's guitar solo on some 2004 concert dates. When queried about the Other Half tour, Eddie said Anthony could "do what he wants" now. This shocked and offended many fans. In November, Eddie's spokesperson, Janie Liszewski, claimed the Van Halen family was writing/rehearsing for a summer 2007 tour, which Billboard magazine's website shortly confirmed. However, the Van Halen website remained in the state it had been in since the Hagar reunion.
On December 11, 2006, Eddie stated to Guitar World magazine that Roth had been directly invited to rejoin the band. However, on December 28, Roth announced that he had not talked to Eddie in two years, and a reunion with Van Halen could result in a "Jerry Springer-style fight."
In January 2007, Van Halen was inducted into the Rock and Roll Hall of Fame. The Van Halen brothers, Anthony, Hagar, and Roth were inducted, though only Hagar and Anthony appeared at the induction ceremony on behalf of the group. Eddie Van Halen was in rehab at the time, so neither he nor Alex attended the ceremony. Velvet Revolver had been slated to perform "You Really Got Me" with Roth on lead vocals. However, Roth wanted to perform "Jump" and the band hadn't rehearsed that song, so Roth elected to not attend the ceremony at all, and Velvet Revolver performed "Ain't Talkin' 'Bout Love". Anthony and Hagar performed "Why Can't This Be Love" with Paul Shaffer. Billboard announced on January 24, 2007, that Van Halen would reunite with Roth for a U.S. tour. This was confirmed shortly after on the official Van Halen website.
The Van Halen News Desk announced on February 15, 2007, that a Van Halen Best Of (1978–1984), a single-disc compilation of the Roth era, would be released by April 3. Shortly after, information arrived in a flood. Various sources claimed the tour was shut down as was the new Best Of CD. On March 8, 2007, Eddie announced on Van Halen's website that he was in rehab. Along with the announcement, a change was made to the website. The logo at the top of the page changed to the original Van Halen logo from their 1978 debut album.
On April 21, 2007, Eddie served as an Honorary Race Official for the NASCAR race at Phoenix International Raceway. On May 24, he posted a note to the Van Halen website confirming that he had completed rehab successfully.
After nearly 10 months of speculation and rumors, Van Halen (and Roth separately via his own website) said that the band would be going on a tour of North America. Roth claimed in the press release that, "the idea is that this will continue on and on and on" and also that a world tour and a new album were both in the works.
Press reaction to the reunion was largely warm, but the re-designed website sparked controversy when Anthony was removed from images of old album artwork. The album covers were restored to their original condition a day later without a word. Wolfgang claimed in 2020 that the omission of Anthony on the website was a choice made by the band's marketing team and was done without consent of the band. Once the band discovered the condition of the website, they ordered it be reverted to its original state. The Fall 2007 tour was originally 25 dates, but was extended into 2008 with a second leg.
Van Halen started their new tour on September 27, 2007, in Charlotte, North Carolina. Playing to sellout crowds, the tour generated positive reviews. Amid rumors of Eddie being back in rehab, multiple dates of the tour were postponed. The official reason was the need for medical procedures to be run on Eddie.
On March 5, 2008, World Entertainment Weekly to CBS News reported that the reason the tour had been interrupted was Eddie's needing to reenter rehab. The report also indicated that it had been a "furious backstage bust-up in Florida with his 17-year-old son and bandmate Wolfgang" which had motivated Eddie to seek help once again.
In response to rumors about Eddie being back in rehab Valerie Bertinelli said that "he is not in rehab." She did not, however, say if he had recently been in rehab, stating only that he was not currently, a statement echoed by Wolfgang during the 2008 Kids Choice Awards. The tour started back up on April 17 at the Reno Events Center in Nevada.
The tour ended on June 2, 2008, at the Van Andel Arena in Grand Rapids, Michigan. During the show Roth stated multiple times that this would not be their final show and that they would "see everyone next time." At this show the arena sign was altered to read "VAN HALEN ARENA". According to the Van Halen News Desk, the reunion tour with Roth was the highest grossing in the band's history, raking in almost $93 million.
On July 3, 2008, Van Halen headlined the Quebec City Summer Festival in front of a crowd of 85,000.