Voice cast
Steven Yeun as Boaz "Bo" – A young mill donkey who is loyal yet worrisome. He sees the star one night thinking it is a sign that his life is soon to change. When he hears of the Royal Caravan marching into Nazareth, he feels this is his purpose and escapes to try to join it. But when he encounters Mary, he feels more dedicated to be with her and keep her out of danger.
Zachary Levi as Joseph – A usually-pessimistic and paranoid young Hebrew carpenter whom Mary weds, soon to be the personal legal guardian of Jesus.
Gina Rodriguez as Mary – A loving and caring young Hebrew woman and soon to be the Mother of Jesus, the Son of God.
Keegan-Michael Key as Dave – A smug and eccentric dove who is Bo's best friend. He joins Bo on his quest to join the Royal Caravan but is more set on that than he is at helping others.
Aidy Bryant as Ruth – A light-hearted, bubbly, and naïve sheep who left her flock to follow the star. She later joins Bo and Dave on their journey to Bethlehem with Mary and Joseph. At first, she seems to be a nuisance to them, but Bo later grows a soft spot for her and soon becomes friends with her.
Ving Rhames as Thaddeus – A sinister captive purebred wolf who is determined to find Jesus for his master.
Gabriel Iglesias as Rufus – An alaunt who is a dimwitted sidekick to Thaddeus.
Christopher Plummer as King Herod – The selfish, treacherous, greedy, and sinister king of Judea who hears about the new King who is arriving and sends the three wise men out to find him in Bethlehem while secretly sending his hunter to find and kill Mary.
Tyler Perry as Cyrus – The intelligent and calm but skeptical leader of the three camels.
Tracy Morgan as Felix – The youngest of the three camels. He is shown to be rather goofy and loudmouthed, and often gets into arguments with Cyrus.
Oprah Winfrey as Deborah – The only female of the three camels. She is the most down-to-earth of the trio, but the other two often think she is crazy despite her attempts at being the voice of reason and keeping her cohorts from making bad choices.
Lex Lang as The Hunter – A large, sinister, yet silent hunter whom King Herod sends out to kill the new King.
Patricia Heaton as Edith – A cow who lives at the stable where Mary and Joseph eventually end up. She is the most level-headed of the animals who reside at the stable and is mostly unamused and pessimistic.
Kelly Clarkson as Leah – A horse who lives at the stable where Mary and Joseph eventually end up. She loves to sing, but more often than not, her singing is obnoxiously loud, which is most likely caused by her lack of sleep since the star began to shine over the stable.
Anthony Anderson as Zach – A goat who lives at the stable where Mary and Joseph eventually end up. He has deformed eyes and is very hyper and paranoid due to the lack of sleep he got since the star began to shine over the stable.
Kristin Chenoweth as Abby – A pygmy jerboa who first witnesses the Angel coming to Mary. She tells her friends about it and tries to warn the others about the hunter.
Mariah Carey as Rebecca – A chicken at a coop.
Kris Kristofferson as The Old Donkey – Bo's fellow elderly mill donkey.
Phil Morris as The Miller – Bo's former owner who is determined to get him back after he escaped from his mill.
Joel McCrary as The Angel – The Holy Spirit who tells Mary that she will soon be carrying the Son of God.
McCrary also voices Zachariah, Elizabeth's husband and John's father.
Joel Osteen as Caspar – One of the three wise men wearing red and Deborah's owner.
Phil Morris as Balthazar – One of the three wise men wearing purple and Cyrus' owner.
Fred Tatasciore as Melchior – One of the three wise men wearing blue and Felix's owner.
Tatasciore also voices a pottery vendor and an innkeeper.
Delilah as Elizabeth – Zachariah's wife and John's mother.
Roger Craig Smith as The Chamberlain
Joe Whyte as A Scribe
Will Townsend as A Horse and a Goat.
Gregg Berger, Roger Craig Smith, Melissa Sturm and Joe Whyte as The Innkeepers.
