Plot
Stu Price plans to travel to Thailand for his upcoming wedding to Lauren, his fiancée. To avoid what happened in Las Vegas two years earlier, Stu does not allow his three best friends, Doug Billings, Phil Wenneck and Alan Garner to throw him a bachelor party. He instead hosts his bachelor party at IHOP with Phil and Doug.
Tracy convinces Doug to persuade Stu to let her brother Alan join their trip to Thailand. Stu agrees to bring his friends, including Alan, Tracy, and Phil's wife Stephanie. At the airport, Lauren's 16-year-old brother Teddy, a Stanford scholar, joins them, to Alan's disapproval.
During the rehearsal dinner, Lauren's father Fong expresses disapproval of Stu in a toast. Later, Stu joins Phil, Doug, Alan, and Teddy for beers around a campfire, toasting to Stu and Lauren's future happiness.
The next day, Phil, Stu, and Alan wake in a rundown Bangkok hotel room with no memory of how they got there. Stu has a face tattoo, Alan's head is shaved, and a capuchin monkey is in the room with them. They discover that Chinese gangster Leslie Chow followed them to Thailand on Alan's invite and can't find Teddy, only his severed finger. Chow begins recounting the previous night but passes out after snorting cocaine. Thinking he's dead, the panicked trio hides his body in the hotel's ice box.
Through a tip from Doug (who left the campfire earlier and stayed at the resort), they go to a police station to pick up Teddy, but are given a wheelchair containing an elderly Buddhist monk. He cannot reveal anything, having taken a vow of silence. After finding a business card, they travel to the smoldering ruins of a business, apparently destroyed in a riot the night before.
They enter a nearby parlor where Stu got his tattoo, and they learn that they started a fight that escalated into the riot. The trio returns the monk to his temple, where they are encouraged to meditate. Alan eventually recalls that they had been at a strip club, where they learn that Stu had sex with a trans woman. Upon exiting, the trio is attacked by two Russian mobsters who shoot Phil in his arm and take the monkey, which originally belonged to them.
After Phil is treated at a clinic, Alan confesses that he had drugged some of the marshmallows with muscle relaxers and his ADHD medication to sedate Teddy, but accidentally mixed up the bags. Furious, Stu attacks Alan.
During the scuffle, they find an address and time for a meeting on Alan's stomach. They meet Kingsley, a gangster demanding Chow's bank password by morning for Teddy. They seek Chow's password at the hotel, discovering he is still alive. They steal back the monkey, who has the code in his vest, and escape through a car chase in which the monkey is shot and injured.
After taking the code and leaving the monkey outside a veterinary, the group completes the deal with Kingsley the next morning. Interpol agents appear and arrest Chow. Kingsley, who reveals himself to be an undercover agent, does not know where Teddy is.
Desperate, Phil calls Tracy to say that they cannot find Teddy. During a rolling blackout, Stu realizes where Teddy is. The trio returns to the hotel to find Teddy in the elevator (though he still misses a finger). He had woken up earlier than the others, but became trapped after the power went out when he left to find ice for his finger. Using Chow's speedboat, the four return to the wedding reception.
Fong is about to cancel the wedding when Stu arrives, delivers a defiant speech, and insists he's wild, impressing Fong, who gives his blessing. At the reception, Alan gifts Stu a performance by Mike Tyson. Later, Teddy reveals he took pictures on his phone before the battery died. The group agrees to view the photos once before deleting them.