Television and film
Her first substantial role in either film / motion pictures or television was as the character Olivia Walton, the wife of John Walton, Sr. on The Waltons drama / nostalgia television series, which ran for nine seasons from 1972 to 1981. For the first five seasons of the show she was billed as "Miss Michael Learned" because she was relatively unknown at the time and producers wished to avoid confusion among viewers about her gender. By the sixth season, as the show continued its success after the departure of co-star Richard Thomas (born 1951), these concerns had been alleviated and the "Miss" was dropped from Learned's billing in the credits. She was nominated for six Emmy Awards as Lead Actress in a Drama, winning three times. After the end of the sixth season, she agreed to appear for one more season on the condition that she would not have to work the full nine months schedule. After the seventh season she left the show. Her character's abrupt disappearance in Season 7 was explained by Olivia developing tuberculosis and entering a sanatorium in hot and dry Arizona. She returned briefly in Season 8 and later appeared in four of the six subsequent Waltons sequel / reunion made-for-TV films and specials made, with three during 1982 and during the 1990s (1993, 1995 and 1997). For her portrayal of Olivia Walton, Learned was also nominated for four Golden Globe Awards. During her run as Olivia Walton, Learned and The Waltons co-star, Will Geer, also appeared together in the 1974 made-for-TV movie Hurricane.
Learned made her big screen debut in 1980, playing the supporting role in the drama film Touched by Love. She later appeared in Power (1986) and Dragon: The Bruce Lee Story (1993), and well as number of made-for-television movies. Learned starred as Nurse Mary Benjamin in the hospital drama Nurse, which ran on the CBS-TV network for six episodes in the spring 1981 and then for the following 1981–1982 seasons. Though the series was well received critically, it was not a big ratings success and lasted only two partial seasons. Nevertheless, Learned was nominated for two Emmy Awards for Outstanding Lead Actress and won yet another Emmy for this role in 1982. She later had starring roles in the unsuccessful 1988 series drama Hothouse and the 1989 sitcom Living Dolls and reprised her Waltons role for a number of television movies and reunions in the 1990s. In 1995, during the second season of The Secret World of Alex Mack, she guest-starred as a ghost who regretted the decisions of her long-estranged granddaughter, revealed at the end to be the show's main villain, Danielle Atron (Louan Gideon). In 2005, Learned played Judge Helen Turner on the ABC-TV network's daytime soap operas All My Children and One Life to Live as part of the "baby switch" storyline on both shows. She guest-starred in Scrubs as Mrs. Wilk in five episodes from the show's fifth season. She played Shirley Smith on ABC's other long-running soap opera General Hospital in 2010. In late 2011, Learned played Katherine Chancellor on the CBS daytime soap opera, The Young and the Restless, filling in for longtime actress Jeanne Cooper, who was on extended medical leave from the series. In 2022, Learned returned to television with starring role in the Netflix limited series, Dahmer – Monster: The Jeffrey Dahmer Story playing Catherine Dahmer, Jeffrey Dahmer's grandmother.