Career
Kazan made her Broadway debut in 1961 with the musical The Happiest Girl in the World. She appeared the following year in another musical, Bravo Giovanni, and understudied Barbra Streisand for the lead role of Fanny Brice in Funny Girl (1964). When Streisand could not perform due to a throat condition, Kazan took her place in a matinee and evening performance for one day of the show's run. Her popularity increasing, Kazan posed nude for the October 1970 issue of Playboy, which was reused in Pocket Playboy #4, issued in 1974. Her appearance in the magazine opened the door for her to headline and operate two different Playboy Jazz Clubs. Overseen by Hugh Hefner, the clubs were named Lainie's Room West and Lainie's Room East, each on opposite coasts, with the first one located in Los Angeles and the other in Manhattan. Her Playboy photographs inspired the look of Jack Kirby’s superheroine Big Barda.
Along with appearing in numerous supper clubs across the country, Kazan guest-starred on Dean Martin's variety series 26 times. Other television work includes a recurring role as Aunt Frieda on the Fran Drescher sitcom The Nanny, the mother of Kirstie Alley's character on Veronica's Closet, and various guest roles, including one on St. Elsewhere that resulted in an Emmy nomination. Her other television work has included The Paper Chase, Columbo, Touched by an Angel, and Will & Grace.
Kazan played Maria Portokalos, the mother of Toula Portokalos (Nia Vardalos) in the My Big Fat Greek Wedding franchise. Following the first film in the franchise, Kazan was featured in My Big Fat Greek Life, a short-lived series based on the film series. Other recent film work includes the mother of Adam Sandler’s character in I Now Pronounce You Chuck and Larry. Although the scene was deleted in the feature film, it is included on the DVD in the special features section. Kazan appeared as singer Ava St. Clair with Kevin James in two episodes of The King of Queens.
A life member of The Actors Studio, Kazan returned to Broadway to re-create her film role for the musical adaptation of My Favorite Year, earning a Tony Award nomination for her performance. She completed a stint in The Vagina Monologues. She has appeared in regional productions of A Little Night Music, Man of La Mancha, Gypsy, Who's Afraid of Virginia Woolf?, Hello, Dolly!, and Fiddler on the Roof. In 1984, she made a guest appearance on the Faerie Tale Theatre episode “Pinocchio” as Sophia the Blue Fairy.
In the Ugly Betty episode "Fire and Nice," Kazan played Dina Talercio, the mother of Bobby (Adam Rodriguez), who becomes the character's brother-in-law. In 2010, Kazan joined the cast of Desperate Housewives for season 7. She played the role of Mrs. Maxine Rosen, a self-employed business owner and neighbor to Susan Delfino.