Solo career
Vaughan released his first solo album, Strange Pleasure, in 1994. The album contained a song "Six Strings Down" that was dedicated to the memory of his brother. He has continued his solo career since then. Vaughan's solo albums contain mostly blues-rock material that he writes himself. He made a special guest appearance on Bo Diddley's 1996 album A Man Amongst Men, playing guitar on the tracks "He's Got A Key" and "Coatimundi". In 2001, Vaughan paid an installment on his (and the Fabulous Thunderbirds') debt to harmonica swamp blues when he contributed guitar to the Lazy Lester album Blues Stop Knockin.'
Since 1997 Fender has produced a Jimmie Vaughan Tex-Mex Stratocaster. Vaughan appeared in the 1998 released film Blues Brothers 2000 as a member of the fictional "Louisiana Gator Boys" blues band led by B. B. King. Vaughan was the third opening act for most of the dates of Bob Dylan's summer 2006 tour, preceded by Elana James and the Continental Two and Junior Brown.
Vaughan continues to perform. Shout! Factory released his first new album in nine years, Plays Blues, Ballads & Favorites, on July 6, 2010.
Also in 2010, he appeared as a guest musician on Eric Johnson's album Up Close, and he played with Eric Clapton, Robert Cray, BB King, Hubert Sumlin, and others during the Crossroads Guitar Festival. He also performed on the episode of the TBS cable television show Conan, that aired December 22, 2010.
Vaughan performed at the 11th Edition of the Rochester International Jazz Festival on Friday, June 29, 2012.
In 2014, Vaughan performed at the Mahindra Blues Festival in India alongside the Tedeschi Trucks Band.
Vaughan appeared and performed as a guest on an episode of the PBS cable television show Austin City Limits, with the Foo Fighters, which aired on February 7, 2015. He and the Foo Fighters were accompanied on stage by another guest guitarist, Gary Clark, Jr., a native of Austin, Texas.
His 2019 recording, Baby, Please Come Home, was chosen as a 'Favorite Blues Album' by AllMusic.
Vaughan performed with Bob Dylan in Austin, Texas on April 6, 2024, as a guest guitarist. He replaced Doug Lancio on nine songs.
Vaughan on 9/11/2026 will be on stage with Eric Clapton performing at the United Center in Chicago, IL.
