Act II
In 1789, Thomas Jefferson returns to America from being the U.S. ambassador to France, taking up his newfound position as Secretary of State ("What'd I Miss"). Jefferson and James Madison debate against Hamilton's financial proposals at a Cabinet meeting. Washington orders Hamilton to figure out a compromise to push his plan through Congress ("Cabinet Battle #1"). Eliza and her family—along with Angelica, visiting from London—travel upstate during the summer, while Hamilton stays home to work on the compromise ("Take a Break"). Hamilton begins an affair with Maria Reynolds, making him vulnerable to her husband's extortion ("Say No to This"). Hamilton, Jefferson, and Madison finally reach a compromise over a private dinner: they will push through Hamilton's financial plan in exchange for placing the country's permanent capital on the Potomac River. Burr is envious of Hamilton's sway in the government and wishes that he had similar power ("The Room Where It Happens"). Burr switches political parties and defeats Hamilton's father-in-law Philip Schuyler in a race for the Senate, now making Hamilton a rival ("Schuyler Defeated").
In another Cabinet meeting, Jefferson and Hamilton argue over whether the United States should assist France in its conflict with Britain. President Washington ultimately agrees with Hamilton's argument for remaining neutral ("Cabinet Battle #2"). In the wake of this, Jefferson, Madison, and Burr decide to join forces to find a way to discredit Hamilton ("Washington on Your Side"). Washington retires from the presidency after his second term, and Hamilton assists in writing his farewell address ("One Last Time"). A flabbergasted King George receives word that George Washington has stepped down, and will be replaced by John Adams ("I Know Him"). Adams fires Hamilton, who, in response, publishes an inflammatory critique of the new president ("The Adams Administration").
Jefferson, Madison, and Burr confront Hamilton about James Reynolds's blackmail years earlier, accusing him of embezzlement ("We Know"). Desperate to salvage his political career by proving that he was merely lustful and not corrupt, Hamilton reminisces over his life and how writing has always saved him ("Hurricane"), before preemptively publicizing his affair in the Reynolds Pamphlet, which wrecks his own reputation ("The Reynolds Pamphlet"). It also ruins his relationship with Eliza, who, in heartbroken retaliation, burns all the letters Hamilton wrote her, trying to erase herself from history ("Burn"). At 19 years old, Hamilton's son Philip attempts to defend his father's honor in a duel with George Eacker ("Blow Us All Away"), but is fatally shot ("Stay Alive (Reprise)"), eventually leading to reconciliation between Alexander and Eliza ("It's Quiet Uptown").
Hamilton's surprising endorsement of longtime political enemy Jefferson over Burr in the 1800 presidential election ("The Election of 1800") dramatically intensifies the animosity between Hamilton and Burr, who reaches his breaking point and challenges Hamilton to a duel via an exchange of letters ("Your Obedient Servant"). Hamilton writes his last letter in a rush while Eliza tells him to go back to bed ("Best of Wives and Best of Women"). Burr reflects on the events leading up to the duel, while Hamilton reflects on his legacy, before firing his bullet up in the air. Burr fatally shoots Hamilton, and laments that though he survived, he is destined to be remembered by history as the villain who killed Hamilton ("The World Was Wide Enough"). The musical closes with a reflection on historical memory. Jefferson and Madison reflect on Hamilton's legacy, while Eliza tells how she reinserted herself in history and ensured Hamilton's memory by recording the memories of fellow veterans, raising funds for the Washington Monument, speaking out against slavery, and establishing the first private orphanage in New York City ("Who Lives, Who Dies, Who Tells Your Story"). Finally, alone on stage, Eliza turns toward the audience and quietly weeps.