FLY is a family of phenethylamine and benzofuran psychedelics possessing a benzodifuran or similar ring system. The FLY drugs were so-named because of the resemblance of their chemical structures to flying insects like dragonflies and butterflies. They are analogues of 2,5-dimethoxyphenethylamines in which the 2- and 5-position methoxy groups have been cyclized into furan and/or tetrahydrofuran rings. They may be 2C, DOx, 25-NB, or other FLY versions of psychedelic phenethylamines.
Examples of different types of FLY drugs, in the case of the base psychedelic 2C-B, include 2C-B-FLY, 2C-B-DragonFLY, and 2C-B-ButterFLY, among others. BromoDragonFLY (DOB-DragonFLY) is known for its very high potency and its toxicity in overdose. 2C-B-FLY was Ann Shulgin's favorite psychedelic.
Several of the FLY drugs have been shown to act as potent serotonin 5-HT2 receptor agonists.
Contents
Use and effects
According to Alexander Shulgin, active doses or dose ranges of FLY drugs are 2.5 to 10 mg orally for 2C-B-FLY, 1 mg orally for DOB-FLY, and 100 μg intramuscularly for Bromo-DragonFLY. Other sources provide dose ranges of 0.2 to 0.8 mg orally for Bromo-DragonFLY, 1 mg orally for DOB-FLY, and 10 to 20 mg for 2C-B-FLY. For comparison, 2C-B has a dose range of 12 to 24 mg orally while DOB has a dose range of 1 to 3 mg orally.
History
The FLY drugs were first described in the scientific literature by Aaron Phillip Monte and David E. Nichols and colleagues at Purdue University by 1995.
List of FLY drugs
2C FLY drugs
2C-B-FLY
2C-B-ButterFLY (2C-B-MOTH)
2C-B-DragonFLY (2C-B-DFLY)
2C-B-5-hemiFLY
2C-C-FLY
2C-I-FLY
2C-DFLY (2C-H-DragonFLY; 2C-H-DFLY)
2C-D-FLY
2C-E-FLY
2C-EF-FLY
2C-T-7-FLY
DOx FLY drugs
Bromo-DragonFLY (DOB-Dragonfly; DOB-DFLY)
DOB-ANTH
DOB-FLY (3C-B-FLY)
DOB-2-DragonFLY-5-ButterFLY
DOB-5-hemiFLY (bromo-semi-FLY; B-SF)
DOB-ButterFLY (DOB-MOTH)
DOH-5-hemiFLY (semi-FLY; SF)
DOI-2-hemiFLY
DOM-FLY
DOMOM-FLY
DragonFLY (DFLY; DOH-FLY)
FLY (DOH-FLY)
TFMFly (TFM-FLY; DOTFM-FLY)
25-NB FLY drugs
2C-B-Fly-NBOMe (NBOMe-2CB-Fly)
2C-B-DragonFLY-NBOH
2C-B-FLY-NB2EtO5Cl
Cyclized FLY drugs
2C-B-5-hemiFLY-α6 (BNAP)
2CB7 (2C-B-5-hemiFLY-β7)
Other FLY drugs
Diaza-2C-DFLY
Hemi-flyscaline (mescaline-hemiFLY)
Mescaline-FLY (flyscaline)
Related compounds
9-Aminomethyl-9,10-dihydroanthracene (AMDA)
F (F-1; 5-methoxy-6-APDB)
