Personal life
Vedder attended San Dieguito High School, now called San Dieguito Academy, and donated proceeds from a 2006 Pearl Jam concert in San Diego toward the construction of a theater for the school in the name of his former drama teacher, Clayton E. Liggett. Liggett was Vedder's mentor in high school. Vedder wrote the song "Long Road" (from Merkin Ball) upon hearing of Liggett's death in 1995.
While living in the basement of Pearl Jam manager Kelly Curtis' house in Seattle in the early 1990s, Vedder was roommates with Alice in Chains guitarist and vocalist Jerry Cantrell. Vedder was also friends with Alice in Chains' lead singer Layne Staley, and wrote the song "4/20/02" (from Lost Dogs) on the night that he found out about Staley's death, on April 20, 2002 (though Staley had died over two weeks earlier on April 5, his body was found on April 19). Vedder also paid tribute to Staley during a Pearl Jam show in Chicago on August 22, 2016, which would have been Staley's 49th birthday; "It's the birthday of a guy called Layne Staley tonight, and we're thinking of him tonight too. 49 years old", Vedder told the crowd before dedicating the song "Man of the Hour" to his late friend.
In 1994, Vedder married Hovercraft bass player Beth Liebling, whom he had dated since he was a teenager, circa 1984. Vedder was Hovercraft's drummer during their opening slot for Mike Watt's U. S. tour in 1995. The couple divorced in September 2000. In an interview published in the June 29, 2006, edition of Rolling Stone magazine, Vedder said that his divorce from Liebling had devastated him. The divorce happened around the same time as an incident where nine fans were crushed to death during Pearl Jam’s set at the Roskilde Festival in Denmark on June 30, 2000. In an interview with Chris Cornell's daughter Lily in 2020, Vedder explained that their show started on a high because they had just been told about her birth, until about 40 minutes into their performance when the tragedy happened. Vedder revealed that Pete Townshend helped him through the early stages of dealing with the tragedy.
On September 18, 2010, Vedder married his longtime girlfriend, model Jill McCormick, whom he had been dating since 2000. They have two daughters, born in 2004 and in 2008. In 2011, McCormick appeared in the music video for Vedder's solo single, "Longing to Belong". In 2014, Vedder and McCormick co-founded the EB Research Partnership, a non-profit organization dedicated to finding a cure for the genetic skin disorder epidermolysis bullosa. They have raised over US$25 million to fund research to find a cure.
Vedder was a close friend of Chris Cornell, the Soundgarden and Audioslave frontman. Aside from Vedder's Pearl Jam bandmates, Cornell was one of the first people Vedder met after moving to Seattle in 1990. The two were neighbors for a while and shared vocal duties in Temple of the Dog. In the 2009 book Grunge Is Dead: The Oral History of Seattle Rock Music, Soundgarden manager Susan Silver recalled that Cornell carried Vedder onstage on his shoulders at Pearl Jam's second show in Seattle (the band was known as Mookie Blaylock at the time): "Everyone was still reeling from [Andrew Wood]'s death... The band came on and Chris carried Eddie onto the stage – he was on his shoulders. It was one of those super powerful moments, where it was all a big healing for everybody. He came out as this guy who had all the credibility in the world – in terms of people in Seattle – and Malfunkshun and Mother Love Bone were loved bands. Andy was such an endearing personality. It was a hard thing to do – to show up after people die. And Chris bringing Eddie out, and pointing at him, as much." Pearl Jam lead guitarist Mike McCready recalled that Cornell had helped welcome the "'super, super shy'" Vedder to Seattle: "He was like, 'Hey, welcome to Seattle. I love Jeff [Ament] and Stone [Gossard]. I give you my blessing". From then on [Vedder] was more relaxed. It was one of the coolest things I saw Chris do'". In a 2009 interview with Uncut magazine, Vedder stated that Cornell is "the best singer that we've got on the planet". About the impact that Cornell had in his life, Vedder told a crowd in Alpine Valley before performing "Hunger Strike" with him in September 2011; "I had no idea how he would affect my life and my views on music and my views on friendship and what a big impact he would have. These guys [the other members of Pearl Jam] know him much longer than me and his impact is profound". The friendship between Vedder and Cornell is featured in the 2011 documentary Pearl Jam Twenty. During his solo concert in London on June 6, 2017, Vedder talked for the first time about Cornell since his death on May 18, 2017, saying that "he wasn't just a friend, he was someone I looked up to like my older brother" and "I will live with those memories in my heart and I will love him forever".
Vedder is a friend of The Who guitarist Pete Townshend, who discouraged Vedder from retiring in 1993. In late 2007, Vedder wrote the foreword to a new Pete Townshend biography, Who Are You: The Life of Pete Townshend. The book was published in the U. K. in March 2008 and in the U. S. in October 2008. Vedder was a close friend of Ramones guitarist Johnny Ramone, with Vedder being at his side when he died. Since Ramone's death, Vedder and Pearl Jam have played the Ramones' "I Believe in Miracles" regularly at live shows. While driving home from Ramone's funeral, Vedder wrote the lyrics for the Pearl Jam song "Life Wasted" (from Pearl Jam).
Vedder was a close friend of Irish musician Glen Hansard, collaborating and touring with him several times, and performed at Hansard's funeral.
While surfing with Tim Finn in New Zealand on March 25, 1995, Vedder was carried 250 feet (76 m) off the coast and had to be rescued by lifeguards. He has also paddled outrigger canoes on occasion and in 2005 was nearly lost at sea trying to paddle from Molokaʻi to Oʻahu.
Vedder has written songs and lyrics that question religious authority.
Vedder is a Chicago Bulls and Chicago Bears fan and a long-time, die-hard fan of the Chicago Cubs. In November 1993, Vedder and White Sox pitcher Jack McDowell were involved in a barroom brawl in New Orleans, Louisiana, that resulted in Vedder being arrested for public drunkenness and disturbing the peace. Vedder sang the national anthem before the third game of the 1998 NBA Finals in Chicago, and has sung "Take Me Out to the Ball Game" at six Cubs games, including Game 5 of the 2016 World Series. In 2007, a few days before performing with Pearl Jam in Chicago for Lollapalooza, he threw out the first pitch at Wrigley Field, the home of the Cubs. Vedder wrote a song at the request of former Cubs shortstop and first baseman Ernie Banks paying tribute to the Cubs called "All the Way". The day after the Cubs won the 2016 World Series, the Cubs' official Twitter account posted a montage video backed by Vedder's song in a tribute to Cubs fans.
The annual baseball series between the Seattle Mariners and San Diego Padres is often nicknamed the Vedder Cup due to both cities being hometowns of the singer. The partnership with Vedder became official in 2025, when Vedder designed a trophy to be given to the winner of the series, while the two teams agreed to support Vedder's charity, the EB Research Partnership, in return.
Vedder is an admirer of the American science fiction author Kurt Vonnegut. During an interview with Uncut, he stated that the novel Cat's Cradle is his favorite book.