24: Season 2
Over a year later, David Palmer is now U.S. president. He is alerted to the threat of a nuclear bomb detonating in the U.S. He also is informed that Bauer, now an inactive agent, has contacts with people who could lead them to the bomb. Jack ignores calls from CTU, but responds to the call from President Palmer. Jack becomes an active agent again, eventually finding the bomb and detonating it in a remote area. Palmer orders attacks on the three nations responsible, as revealed by an audio known as the Cyprus Recording. Palmer then reverses course, stating that he believes the recordings to be fake, as advised by Jack, but Mike Novick, his Chief of Staff, and the vice president, Jim Prescott deem this sudden reluctance to attack as an incapability to hold the office. Prescott gathers the Cabinet members, and by one vote, David Palmer is removed from office under the provisions of the 25th Amendment. He sits in a room as a prisoner for the rest of the day, until Jack provides CTU with the evidence that the Cyprus Recording is a forgery, and the attacks are called off by Prescott.
Palmer is reinstated as president, and although Prescott and the Cabinet members who voted against Palmer offer to resign, he does not accept their resignations. Palmer does, however, immediately relieve Mike Novick of his post as chief of staff. Palmer then goes out to make a statement to the press, deeming that the threat is over. He shakes hands with many of the onlookers, one of whom happens to be Mandy, a woman hired in Day 1 to assassinate Palmer. She slips a deadly virus into his hand, and he collapses to the ground, panting.
(The extended ending presented in the 24 Season 2 boxset has him get up and say he's all right; this was filmed to stop the extras on location from leaking the real ending.)