1947–1955: Early theatre and film roles
After the war, the Hestons lived in Hell's Kitchen, New York City, where they worked as artists' models. Seeking a way to make it in theatre, they decided to manage a playhouse in Asheville, North Carolina, in 1947, making $100 a week (roughly equivalent to $1,400 in 2025). In 1948, they returned to New York, where Heston was offered a supporting role in a Broadway revival of Shakespeare's Antony and Cleopatra, starring Katharine Cornell. In television, Heston played a number of roles in CBS's Studio One, one of the most popular anthology dramas of the 1950s. In 1949 Heston played Mark Antony in an independent film adaptation of Julius Caesar (1950). Film producer Hal B. Wallis spotted Heston in a 1950 television production of Wuthering Heights and offered him a contract. When his wife reminded Heston they had decided to pursue theater and television, he replied, "Well, maybe just for one film to see what it's like."
Heston's first professional movie appearance was the leading role at age 26 in Dark City, a 1950 film noir produced by Hal Wallis. His breakthrough came when Cecil B. DeMille cast him as a circus manager in The Greatest Show on Earth, which was named by the Motion Picture Academy as the Best Picture of 1952. It was also the most popular movie of that year. King Vidor used Heston in a melodrama with Jennifer Jones, Ruby Gentry (1952). He followed it with a Western at Paramount, The Savage (1952), playing a white man raised by Indians. 20th Century Fox used him to play Andrew Jackson in The President's Lady (1953) opposite Susan Hayward. Back at Paramount Heston was Buffalo Bill in Pony Express (1953). He followed this with another Western, Arrowhead (1953).
In 1953, Heston was Billy Wilder's first choice to play Sefton in Stalag 17. However, the role was given to William Holden, who won an Oscar for it. Hal Wallis reunited Heston with Lizabeth Scott in a melodrama Bad for Each Other (1953). In 1954, he made two adventure films for Paramount Pictures. The Naked Jungle had Heston battle a plague of killer ants. He played the lead in Secret of the Incas, which was shot on location at the archeological site Machu Picchu and has numerous similarities to Raiders of the Lost Ark, which appeared a quarter of a century later. Heston played the explorer William Clark in The Far Horizons (1955) with Fred MacMurray as Meriwether Lewis. Heston tried a comedy The Private War of Major Benson (1955) at Universal, then supported Jane Wyman in a drama Lucy Gallant (1955).
Heston played Moses in the hugely successful biblical epic The Ten Commandments (1956), selected by director Cecil B. DeMille, who thought Heston bore an uncanny resemblance to Michelangelo's statue of Moses. DeMille cast Heston's three-month-old son Fraser Clarke Heston as the infant Moses. The Ten Commandments became one of the greatest box office successes of all time and is the eighth-highest-grossing film adjusted for inflation. His portrayal of the Hebrew prophet and deliverer was praised by film critics. The Hollywood Reporter described him as "splendid, handsome and princely (and human) in the scenes dealing with him as a young man, and majestic and terrible as his role demands it". The New York Daily News wrote that Heston "is remarkably effective as both the young, princely Moses and as the Patriarchal savior of his people". His performance as Moses earned him his first nomination for the Golden Globe Award for Best Actor – Motion Picture Drama and Spain's Fotogramas de Plata Award for Best Foreign Performer. When the Egyptian Theater reopened in December 1998, it screened Cecil B. DeMille's 1923 original The Ten Commandments, which had premiered there 75 years earlier. Charlton and Lydia Heston were honored guests at this opening showing and were seated with their longtime friends, brothers Charles Elias Disney and Daniel H. Disney.
Heston went back to Westerns with Three Violent People (1957). Universal tried to interest him in a thriller starring Orson Welles, Touch of Evil; Heston agreed to be in it if Welles directed. The film has come to be regarded as a masterpiece, despite criticism for Heston playing the role of Mexican prosecutor Mike Vargas in brownface. He also played a rare supporting role in William Wyler's The Big Country opposite Gregory Peck and Burl Ives. Heston had another chance to play Andrew Jackson in The Buccaneer (1958), produced by De Mille and starring Yul Brynner.