Berthold is a German surname. Notable people with the name include:
Arnold Adolph Berthold (1803–1861), German physiologist and zoologist
Avgust Berthold (1880–1919), Slovene photographer
Barbara Metselaar Berthold (1951–2024), German photographer and filmmaker
Daniel Berthold (born 1953), American philosopher
David Berthold, Australian theatre director
Fred Berthold (1922–2019), American theologian and academic
Frederic Berthold (born 1991), Austrian World Cup alpine ski racer
Gerhard Berthold (1891–1942), German general
Helmut Berthold (1911–2000), German handball player
Hermann Berthold (1831–1904), Prussian and German printer
Hermine Berthold (1896–1990), German resistance member and politician
Kate McKinnon Berthold (born 1984)Pages displaying short descriptions of redirect targets, American actress and comedian
Lothar Berthold (1926–2007), German politician, historian and publisher
Luc Berthold (born 1966), Canadian politician
Mathias Berthold (born 1965), Austrian alpine skier
Michael Berthold, German computer scientist
Richard Berthold (born 1946), American historian of ancient Greece
Rudolf Berthold (1891–1920), German WWI flying ace
Rudolf Berthold (footballer) (1903–1976), German footballer
Simón Berthold (died 1911), Mexican anarchist militant
Thomas Berthold (born 1964), German footballer and soccer coach